2D-Nature of Active Brownian Motion at Interfaces published in New J. Phys.

Two-dimensional nature of the active Brownian motion of catalytic microswimmers at solid and liquid interfaces

Two-dimensional nature of the active Brownian motion of catalytic microswimmers at solid and liquid interfaces
Kilian Dietrich, Damian Renggli, Michele Zanini, Giovanni Volpe, Ivo Buttinoni & Lucio Isa
New Journal of Physics 19, 065008 (2017)
DOI: 10.1088/1367-2630/aa7126

Colloidal particles equipped with platinum patches can establish chemical gradients in H2O2-enriched solutions and undergo self-propulsion due to local diffusiophoretic migration. In bulk (3D), this class of active particles swim in the direction of the surface heterogeneities introduced by the patches and consequently reorient with the characteristic rotational diffusion time of the colloids. In this article, we present experimental and numerical evidence that planar 2D confinements defy this simple picture. Instead, the motion of active particles both on solid substrates and at flat liquid–liquid interfaces is captured by a 2D active Brownian motion model, in which rotational and translational motion are constrained in the xy-plane. This leads to an active motion that does not follow the direction of the surface heterogeneities and to timescales of reorientation that do not match the free rotational diffusion times. Furthermore, 2D-confinement at fluid–fluid interfaces gives rise to a unique distribution of swimming velocities: the patchy colloids uptake two main orientations leading to two particle populations with velocities that differ up to one order of magnitude. Our results shed new light on the behavior of active colloids in 2D, which is of interest for modeling and applications where confinements are present.

Langevin Equation on a Manifold published in Ann. Henri Poincaré

Small Mass Limit of a Langevin Equation on a Manifold

Small Mass Limit of a Langevin Equation on a Manifold
Jeremiah Birrell, Scott Hottovy, Giovanni Volpe & Jan Wehr
Annales Henri Poincaré 18(2), 707—755 (2017)
DOI: 10.1007/s00023-016-0508-3
arXiv: 1604.04819

We study damped geodesic motion of a particle of mass m on a Riemannian manifold, in the presence of an external force and noise. Lifting the resulting stochastic differential equation to the orthogonal frame bundle, we prove that, as m → 0, its solutions converge to solutions of a limiting equation which includes a noise-induced drift term. A very special case of the main result presents Brownian motion on the manifold as a limit of inertial systems.

Non-Boltzmann Distributions and Non-Equilibrium Relations in Active Baths published in Phys. Rev. E

Non-Boltzmann stationary distributions and non-equilibrium relations in active baths

Non-Boltzmann stationary distributions and non-equilibrium relations in active baths
Aykut Argun, Ali-Reza Moradi, Erçağ Pinçe, Gokhan Baris Bagci, Alberto Imparato & Giovanni Volpe
Physical Review E 94(6), 062150 (2016)
DOI: 10.1103/PhysRevE.94.062150

Most natural and engineered processes, such as biomolecular reactions, protein folding, and population dynamics, occur far from equilibrium and therefore cannot be treated within the framework of classical equilibrium thermodynamics. Here we experimentally study how some fundamental thermodynamic quantities and relations are affected by the presence of the nonequilibrium fluctuations associated with an active bath. We show in particular that, as the confinement of the particle increases, the stationary probability distribution of a Brownian particle confined within a harmonic potential becomes non-Boltzmann, featuring a transition from a Gaussian distribution to a heavy-tailed distribution. Because of this, nonequilibrium relations (e.g., the Jarzynski equality and Crooks fluctuation theorem) cannot be applied. We show that these relations can be restored by using the effective potential associated with the stationary probability distribution. We corroborate our experimental findings with theoretical arguments.

Review on Active Matter published in Rev. Mod. Phys.

Active Brownian particles in complex and crowded environments

Active Brownian particles in complex and crowded environments (Invited review)
Clemens Bechinger, Roberto Di Leonardo, Hartmut Löwen, Charles Reichhardt, Giorgio Volpe & Giovanni Volpe
Reviews of Modern Physics 88(4), 045006 (2016)
DOI: 10.1103/RevModPhys.88.045006
arXiv: 1602.00081

Differently from passive Brownian particles, active particles, also known as self-propelled Brownian particles or microswimmers and nanoswimmers, are capable of taking up energy from their environment and converting it into directed motion. Because of this constant flow of energy, their behavior can be explained and understood only within the framework of nonequilibrium physics. In the biological realm, many cells perform directed motion, for example, as a way to browse for nutrients or to avoid toxins. Inspired by these motile microorganisms, researchers have been developing artificial particles that feature similar swimming behaviors based on different mechanisms. These man-made micromachines and nanomachines hold a great potential as autonomous agents for health care, sustainability, and security applications. With a focus on the basic physical features of the interactions of self-propelled Brownian particles with a crowded and complex environment, this comprehensive review will provide a guided tour through its basic principles, the development of artificial self-propelling microparticles and nanoparticles, and their application to the study of nonequilibrium phenomena, as well as the open challenges that the field is currently facing.

Stochastic Differential Delay Equations with Colored State-Dependent Noise published in Markov Processes and Related Fields

An SDE approximation for stochastic differential delay equations with colored state-dependent noise

An SDE approximation for stochastic differential delay equations with colored state-dependent noise
Austin McDaniel, Ozer Duman, Giovanni Volpe & Jan Wehr
Markov Processes and Related Fields 22(3), 595-628 (2016)
arXiv: 1406.7287

We consider a general multidimensional stochastic differential delay equation (SDDE) with colored state-dependent noises. We approxi-mate it by a stochastic differential equation (SDE) system and calcu- late its limit as the time delays and the correlation times of the noises go to zero. The main result is proven using a theorem of convergence of stochastic integrals developed by Kurtz and Protter. The result formalizes and extends a method that has been used in the analysis of a noisy electrical circuit with delayed state-dependent noise, and may be further used as a working SDE approximation of an SDDE system modeling a real system, where noises are correlated in time and whose response to stimuli is delayed.

Disrupted Network Topology in Alzheimer published in Cerebral Cortex

Disrupted Network Topology in Patients with Stable and Progressive Mild Cognitive Impairment and Alzheimer’s Disease

Disrupted Network Topology in Patients with Stable and Progressive Mild Cognitive Impairment and Alzheimer’s Disease
Joana B. Pereira, Mite Mijalkov, Ehsan Kakaei, Patricia Mecocci, Bruno Vellas, Magda Tsolaki, Iwona Kłoszewska, Hilka Soininen, Christian Spenger, Simmon Lovestone, Andrew Simmons, Lars-Olof Wahlund, Giovanni Volpe & Eric Westman, AddNeuroMed consortium, for the Alzheimer’s Disease Neuroimaging Initiative
Cerebral Cortex 26(8), 3476—3493 (2016)
DOI: 10.1093/cercor/bhw128

Recent findings suggest that Alzheimer’s disease (AD) is a disconnection syndrome characterized by abnormalities in large- scale networks. However, the alterations that occur in network topology during the prodromal stages of AD, particularly in patients with stable mild cognitive impairment (MCI) and those that show a slow or faster progression to dementia, are still poorly understood. In this study, we used graph theory to assess the organization of structural MRI networks in stable MCI (sMCI) subjects, late MCI converters (lMCIc), early MCI converters (eMCIc), and AD patients from 2 large multicenter cohorts: ADNI and AddNeuroMed. Our findings showed an abnormal global network organization in all patient groups, as reflected by an increased path length, reduced transitivity, and increased modularity compared with controls. In addition, lMCIc, eMCIc, and AD patients showed a decreased path length and mean clustering compared with the sMCI group. At the local level, there were nodal clustering decreases mostly in AD patients, while the nodal closeness centrality detected abnormalities across all patient groups, showing overlapping changes in the hippocampi and amygdala and nonoverlapping changes in parietal, entorhinal, and orbitofrontal regions. These findings suggest that the prodromal and clinical stages of AD are associated with an abnormal network topology.

Better Stability with Measurement Errors published in J. Stat. Phys.

Better stability with measurement errors

Better stability with measurement errors
Aykut Argun & Giovanni Volpe
Journal of Statistical Physics 163(6), 1477—1485 (2016)
DOI: 10.1007/s10955-016-1518-8
arXiv: 1608.08461

Often it is desirable to stabilize a system around an optimal state. This can be effectively accomplished using feedback control, where the system deviation from the desired state is measured in order to determine the magnitude of the restoring force to be applied. Contrary to conventional wisdom, i.e. that a more precise measurement is expected to improve the system stability, here we demonstrate that a certain degree of measurement error can improve the system stability. We exemplify the implications of this finding with numerical examples drawn from various fields, such as the operation of a temperature controller, the confinement of a microscopic particle, the localization of a target by a microswimmer, and the control of a population.

Nonadditivity of Critical Casimir Forces published in Nature Commun.

Nonadditivity of critical Casimir forces

Nonadditivity of critical Casimir forces
Paladugu Sathyanarayana, Agnese Callegari, Yazgan Tuna, Lukas Barth, Siegfried Dietrich, Andrea Gambassi & Giovanni Volpe
Nature Communications 7, 11403 (2016)
DOI: 10.1038/ncomms11403
arXiv: 1511.02613

In soft condensed matter physics, effective interactions often emerge due to the spatial confinement of fluctuating fields. For instance, microscopic particles dissolved in a binary liquid mixture are subject to critical Casimir forces whenever their surfaces confine the thermal fluctuations of the order parameter of the solvent close to its critical demixing point. These forces are theoretically predicted to be nonadditive on the scale set by the bulk correlation length of the fluctuations. Here we provide direct experimental evidence of this fact by reporting the measurement of the associated many-body forces. We consider three colloidal particles in optical traps and observe that the critical Casimir force exerted on one of them by the other two differs from the sum of the forces they exert separately. This three-body effect depends sensitively on the distance from the critical point and on the chemical functionalisation of the colloid surfaces.

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Review on Multiplicative Noise published in Rep. Prog. Phys.

Effective drifts in dynamical systems with multiplicative noise: A review of recent progress

Effective drifts in dynamical systems with multiplicative noise: A review of recent progress (Invited review)
Giovanni Volpe & Jan Wehr
Reports on Progress in Physics 79(5), 053901 (2016)
DOI: 10.1088/0034-4885/79/5/053901
arXiv: 1511.05340

Noisy dynamical models are employed to describe a wide range of phenomena. Since exact modeling of these phenomena requires access to their microscopic dynamics, whose time scales are typically much shorter than the observable time scales, there is often need to resort to effective mathematical models such as stochastic differential equations (SDEs). In particular, here we consider effective SDEs describing the behavior of systems in the limits when natural time scales become very small. In the presence of multiplicative noise (i.e. noise whose intensity depends upon the system’s state), an additional drift term, called noise-induced drift or effective drift, appears. The nature of this noise-induced drift has been recently the subject of a growing number of theoretical and experimental
studies. Here, we provide an extensive review of the state of the art in this eld. After an introduction, we discuss a minimal model of how multiplicative noise affects the evolution of a system. Next, we consider several case studies with a focus on recent experiments: the Brownian motion of a microscopic particle in thermal equilibrium with a heat bath in the presence of a diffusion gradient; the limiting behavior of a system driven by a colored noise modulated by a multiplicative feedback; and the behavior of an autonomous agent subject to sensorial delay in a noisy environment. This allows us to present the experimental results, as well as mathematical methods and numerical techniques, that can be employed to study a wide range of systems. At the end we give an application-oriented overview of future projects involving noise-induced drifts, including both theory and experiment.

Microscopic Crowd Control published in Nature Commun.

Disorder-mediated crowd control in an active matter system

Disorder-mediated crowd control in an active matter system
Erçağ Pinçe, Sabareesh K. P. Velu, Agnese Callegari, Parviz Elahi, Sylvain Gigan, Giovanni Volpe & Giorgio Volpe
Nature Communications 7, 10907 (2016)
DOI: 10.1038/ncomms10907

Living active matter systems such as bacterial colonies, schools of fish and human crowds, display a wealth of emerging collective and dynamic behaviours as a result of far-from- equilibrium interactions. The dynamics of these systems are better understood and controlled considering their interaction with the environment, which for realistic systems is often highly heterogeneous and disordered. Here, we demonstrate that the presence of spatial disorder can alter the long-term dynamics in a colloidal active matter system, making it switch between gathering and dispersal of individuals. At equilibrium, colloidal particles always gather at the bottom of any attractive potential; however, under non-equilibrium driving forces in a bacterial bath, the colloids disperse if disorder is added to the potential. The depth of the local roughness in the environment regulates the transition between gathering and dispersal of individuals in the active matter system, thus inspiring novel routes for controlling emerging behaviours far from equilibrium.

 

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