John Tember, Harshith Bachimanchi, Tsz Long Chu, Xin Tian, Andrei Chagin, Giovanni Volpe
Date: 11th March 2026
Time: 18:00 – 20:00
Place: Aula Medica, Karolinska Institute, Solna
Conference: Protein Folding in Real Time, 11-13 March 2026, Stockholm, Sweden
We present FIREFLY (Framework for Interactive Rendering, Exploration and Feature Extraction for Light-Sheet Microscopy), a platform for scalable computational tools. Modern 3D microscopy datasets are increasingly large and complex, posing challenges for efficient visualization, processing, and quantitative analysis. Our work focuses on developing tools and methods to support interactive and high-quality analysis workflows.
We are building a Unity-based application for real-time, multi-channel 3D rendering, enabling interactive inspection and quantitative analysis of large volumetric datasets. In parallel, we explore self-supervised machine learning approaches for enhancing anisotropic microscopy volumes and improving resolution without requiring additional training data.
Together, these efforts aim to provide an integrated and scalable pipeline for visualization and analysis in light-sheet microscopy.