Invited talk by S. K. Manikandan at The 15th Nordic Workshop on Statistical Physics, Nordita, 26 Feb 2026

Recent advances in nonequilibrium physics allow extracting thermodynamic quantities, such as entropy production, directly from dynamical information in microscopic movies. (Figure by S. Manikandan, adapted from Manikandan et al., Phys. Rev. Research 6, 023310 (2024).)
Localising Entropy Production and Maximally Dissipative Coordinates from Experimental Data
Sreekanth Manikandan
Date: 26th February 2026
Time: 14.00
Place: NORDITA, Stockholm, Sweden
The 15th Nordic Workshop on Statistical Physics: Biological, Complex and Non-equilibrium Systems

Identifying whether a process is in equilibrium, quantifying how far it lies from equilibrium, and determining optimal reduced descriptions of non-equilibrium processes remain challenging open problems. Here, we discuss how novel data-driven techniques grounded in stochastic thermodynamics can be used to efficiently learn these features directly from experimental data. In particular, we show how entropy production can be localized in space and time, and how maximally dissipative coordinates can be consistently inferred as effective low-dimensional descriptions of non-equilibrium processes. We further discuss applications to experimental biophysical systems and outline key challenges and limitations.

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